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RECOMB
2004
Springer
14 years 4 months ago
Discovering temporal relations in molecular pathways using protein-protein interactions
The availability of large-scale protein-protein interaction data provides us with many opportunities to study molecular pathways involving proteins. In this paper we propose to mi...
Martin Farach-Colton, Yang Huang, John L. L. Woolf...
LBM
2007
13 years 6 months ago
Syntactic Features for Protein-Protein Interaction Extraction
Background: Extracting Protein-Protein Interactions (PPI) from research papers is a way of translating information from English to the language used by the databases that store th...
Rune Sætre, Kenji Sagae, Jun-ichi Tsujii
BMCBI
2008
120views more  BMCBI 2008»
13 years 4 months ago
A protein interaction based model for schizophrenia study
Background: Schizophrenia is a complex disease with multiple factors contributing to its pathogenesis. In addition to environmental factors, genetic factors may also increase susc...
Pei-Chun Hsu, Ueng-Cheng Yang, Kuan-Hui Shih, Chih...
BMCBI
2010
147views more  BMCBI 2010»
13 years 4 months ago
Learning biological network using mutual information and conditional independence
Background: Biological networks offer us a new way to investigate the interactions among different components and address the biological system as a whole. In this paper, a revers...
Dong-Chul Kim, Xiaoyu Wang, Chin-Rang Yang, Jean G...
BMCBI
2010
135views more  BMCBI 2010»
13 years 4 months ago
Detecting disease associated modules and prioritizing active genes based on high throughput data
Background: The accumulation of high-throughput data greatly promotes computational investigation of gene function in the context of complex biological systems. However, a biologi...
Yu-Qing Qiu, Shi-Hua Zhang, Xiang-Sun Zhang, Luona...