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CIKM
2010
Springer
13 years 3 months ago
Discovery of numerous specific topics via term co-occurrence analysis
We describe efficient techniques for construction of large term co-occurrence graphs, and investigate an application to the discovery of numerous fine-grained (specific) topics. A...
Omid Madani, Jiye Yu
BMCBI
2008
84views more  BMCBI 2008»
13 years 5 months ago
Prediction of specificity-determining residues for small-molecule kinase inhibitors
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
Daniel R. Caffrey, Elizabeth A. Lunney, Deborah J....