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BMCBI
2005
102views more  BMCBI 2005»
13 years 5 months ago
Genome-wide identification of the regulatory targets of a transcription factor using biochemical characterization and computatio
Background: A major challenge in computational genomics is the development of methodologies that allow accurate genome-wide prediction of the regulatory targets of a transcription...
Emmitt R. Jolly, Chen-Shan Chin, Ira Herskowitz, H...
HYBRID
2007
Springer
13 years 12 months ago
Model Checking Genetic Regulatory Networks with Parameter Uncertainty
The lack of precise numerical information for the values of biological parameters severely limits the development and analysis of models of genetic regulatory networks. To deal wit...
Grégory Batt, Calin Belta, Ron Weiss
EVOW
2007
Springer
13 years 12 months ago
Modeling the Shoot Apical Meristem in A. thaliana : Parameter Estimation for Spatial Pattern Formation
Understanding the self-regulatory mechanisms controlling the spatial and temporal structure of multicellular organisms represents one of the major challenges in molecular biology. ...
Tim Hohm, Eckart Zitzler
BMCBI
2005
104views more  BMCBI 2005»
13 years 5 months ago
An integrated approach of immunogenomics and bioinformatics to identify new Tumor Associated Antigens (TAA) for mammary cancer i
Background: Neoplastic transformation is a multistep process in which distinct gene products of specific cell regulatory pathways are involved at each stage. Identification of ove...
Federica Cavallo, Annalisa Astolfi, Manuela Iezzi,...
ICDM
2003
IEEE
111views Data Mining» more  ICDM 2003»
13 years 11 months ago
OP-Cluster: Clustering by Tendency in High Dimensional Space
Clustering is the process of grouping a set of objects into classes of similar objects. Because of unknownness of the hidden patterns in the data sets, the definition of similari...
Jinze Liu, Wei Wang 0010