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» Discriminant Analysis and Its Application in DNA Sequence Mo...
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ESANN
2008
13 years 6 months ago
Discrimination of regulatory DNA by SVM on the basis of over- and under-represented motifs
In this paper we apply three pattern recognition methods (support vector machine, cluster analysis and principal component analysis) to distinguish regulatory regions from coding a...
Rene te Boekhorst, Irina I. Abnizova, Lorenz Werni...
JCB
2006
138views more  JCB 2006»
13 years 4 months ago
Recognition and Classification of Histones Using Support Vector Machine
Histones are DNA-binding proteins found in the chromatin of all eukaryotic cells. They are highly conserved and can be grouped into five major classes: H1/H5, H2A, H2B, H3, and H4...
Manoj Bhasin, Ellis L. Reinherz, Pedro A. Reche
BMCBI
2010
113views more  BMCBI 2010»
13 years 4 months ago
Unifying generative and discriminative learning principles
Background: The recognition of functional binding sites in genomic DNA remains one of the fundamental challenges of genome research. During the last decades, a plethora of differe...
Jens Keilwagen, Jan Grau, Stefan Posch, Marc Stric...
BMCBI
2004
207views more  BMCBI 2004»
13 years 4 months ago
Computational identification of transcription factor binding sites by functional analysis of sets of genes sharing overrep-resen
Background: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mostly effected through transcription factors binding to specific recognition moti...
Davide Corà, Ferdinando Di Cunto, Paolo Pro...