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» Discriminatory power of RNA family models
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BIOINFORMATICS
2010
87views more  BIOINFORMATICS 2010»
13 years 4 months ago
Discriminatory power of RNA family models
Motivation: RNA family models group nucleotide sequences that share a common biological function. These models can be used to find new sequences belonging to the same family. To s...
Christian Höner zu Siederdissen, Ivo L. Hofac...
BMCBI
2002
108views more  BMCBI 2002»
13 years 4 months ago
A memory-efficient dynamic programming algorithm for optimal alignment of a sequence to an RNA secondary structure
Background: Covariance models (CMs) are probabilistic models of RNA secondary structure, analogous to profile hidden Markov models of linear sequence. The dynamic programming algo...
Sean R. Eddy
BMCBI
2005
99views more  BMCBI 2005»
13 years 4 months ago
Effective ambiguity checking in biosequence analysis
Background: Ambiguity is a problem in biosequence analysis that arises in various analysis tasks solved via dynamic programming, and in particular, in the modeling of families of ...
Janina Reeder, Peter Steffen, Robert Giegerich