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» Domain Architecture in Homolog Identification
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BMCBI
2005
75views more  BMCBI 2005»
13 years 5 months ago
Prediction of a common structural scaffold for proteasome lid, COP9-signalosome and eIF3 complexes
Background: The 'lid' subcomplex of the 26S proteasome and the COP9 signalosome (CSN complex) share a common architecture consisting of six subunits harbouring a so-call...
Hartmut Scheel, Kay Hofmann
BMCBI
2005
140views more  BMCBI 2005»
13 years 5 months ago
JACOP: A simple and robust method for the automated classification of protein sequences with modular architecture
Background: Whole-genome sequencing projects are rapidly producing an enormous number of new sequences. Consequently almost every family of proteins now contains hundreds of membe...
Peter Sperisen, Marco Pagni
BMCBI
2007
139views more  BMCBI 2007»
13 years 6 months ago
XSTREAM: A practical algorithm for identification and architecture modeling of tandem repeats in protein sequences
Background: Biological sequence repeats arranged in tandem patterns are widespread in DNA and proteins. While many software tools have been designed to detect DNA tandem repeats (...
Aaron M. Newman, James B. Cooper
NAR
2006
77views more  NAR 2006»
13 years 5 months ago
SMART 5: domains in the context of genomes and networks
The Simple Modular Architecture Research Tool 10 (SMART) is an online resource (http://smart.embl. de/) used for protein domain identification and the analysis of protein domain a...
Ivica Letunic, Richard R. Copley, Birgit Pils, Ste...
BMCBI
2010
131views more  BMCBI 2010»
13 years 6 months ago
FACT: Functional annotation transfer between proteins with similar feature architectures
Background: The increasing number of sequenced genomes provides the basis for exploring the genetic and functional diversity within the tree of life. Only a tiny fraction of the e...
Tina Koestler, Arndt von Haeseler, Ingo Ebersberge...