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» Domain boundary prediction based on profile domain linker pr...
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CANDC
2006
ACM
13 years 4 months ago
Domain boundary prediction based on profile domain linker propensity index
Successful prediction of protein domain boundaries provides valuable information not only for the computational structure prediction of multidomain proteins but also for the exper...
Qiwen Dong, Xiaolong Wang, Lei Lin, Zhiming Xu
BMCBI
2008
153views more  BMCBI 2008»
13 years 4 months ago
Improved general regression network for protein domain boundary prediction
Background: Protein domains present some of the most useful information that can be used to understand protein structure and functions. Recent research on protein domain boundary ...
Paul D. Yoo, Abdur R. Sikder, Bing Bing Zhou, Albe...
NAR
1998
86views more  NAR 1998»
13 years 4 months ago
Pfam: multiple sequence alignments and HMM-profiles of protein domains
Pfam contains multiple alignments and hidden Markov model based profiles (HMM-profiles) of complete protein domains. The definition of domain boundaries, family members and alignm...
Erik L. L. Sonnhammer, Sean R. Eddy, Ewan Birney, ...
EMNLP
2007
13 years 6 months ago
Topic Segmentation with Hybrid Document Indexing
We present a domain-independent unsupervised topic segmentation approach based on hybrid document indexing. Lexical chains have been successfully employed to evaluate lexical cohe...
Irina Matveeva, Gina-Anne Levow
BMCBI
2008
178views more  BMCBI 2008»
13 years 5 months ago
A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic ana
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
Bin Liu, Xiaolong Wang, Lei Lin, Qiwen Dong, Xuan ...