Background: Leishmaniasis is a virulent parasitic infection that causes a worldwide disease burden. Most treatments have toxic side-effects and efficacy has decreased due to the e...
Background: Molecular-docking-based virtual screening is an important tool in drug discovery that is used to significantly reduce the number of possible chemical compounds to be i...
Shuxing Zhang, Kamal Kumar, Xiaohui Jiang, Anders ...
Background: In order to recapitulate tumor progression pathways using epigenetic data, we developed novel clustering and pathway reconstruction algorithms, collectively referred t...
Zailong Wang, Pearlly Yan, Dustin P. Potter, Chari...
Assume a uniform, multidimensional grid of bivariate data, where each cell of the grid has a count ci and a baseline bi. Our goal is to find spatial regions (d-dimensional rectang...
Daniel B. Neill, Andrew W. Moore, Francisco Pereir...
—All sciences, including astronomy, are now entering the era of information abundance. The exponentially increasing volume and complexity of modern data sets promises to transfor...