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» DynGO: a tool for visualizing and mining of Gene Ontology an...
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BMCBI
2005
156views more  BMCBI 2005»
13 years 4 months ago
DynGO: a tool for visualizing and mining of Gene Ontology and its associations
Background: A large volume of data and information about genes and gene products has been stored in various molecular biology databases. A major challenge for knowledge discovery ...
Hongfang Liu, Zhang-Zhi Hu, Cathy H. Wu
BMCBI
2010
153views more  BMCBI 2010»
13 years 4 months ago
GOAL: A software tool for assessing biological significance of genes groups
Background: Modern high throughput experimental techniques such as DNA microarrays often result in large lists of genes. Computational biology tools such as clustering are then us...
Alain B. Tchagang, Alexander Gawronski, Hugo B&eac...
BMCBI
2004
142views more  BMCBI 2004»
13 years 4 months ago
GOTree Machine (GOTM): a web-based platform for interpreting sets of interesting genes using Gene Ontology hierarchies
Background: Microarray and other high-throughput technologies are producing large sets of interesting genes that are difficult to analyze directly. Bioinformatics tools are needed...
Bing Zhang, Denise Schmoyer, Stefan Kirov, Jay Sno...
BMCBI
2006
183views more  BMCBI 2006»
13 years 4 months ago
Mining gene expression data by interpreting principal components
Background: There are many methods for analyzing microarray data that group together genes having similar patterns of expression over all conditions tested. However, in many insta...
Joseph C. Roden, Brandon W. King, Diane Trout, Ali...
BMCBI
2010
144views more  BMCBI 2010»
13 years 4 months ago
Identifying overrepresented concepts in gene lists from literature: a statistical approach based on Poisson mixture model
Background: Large-scale genomic studies often identify large gene lists, for example, the genes sharing the same expression patterns. The interpretation of these gene lists is gen...
Xin He, Moushumi Sen Sarma, Xu Ling, Brant W. Chee...