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» Embryonics: Artificial Cells Driven by Artificial DNA
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BMCBI
2007
144views more  BMCBI 2007»
13 years 5 months ago
Accelerated search for biomolecular network models to interpret high-throughput experimental data
Background: The functions of human cells are carried out by biomolecular networks, which include proteins, genes, and regulatory sites within DNA that encode and control protein e...
Suman Datta, Bahrad A. Sokhansanj
ALIFE
2005
13 years 5 months ago
State Aggregation and Population Dynamics in Linear Systems
We consider complex systems that are composed of many interacting elements, evolving under some dynamics. We are interested in characterizing the ways in which these elements may b...
Jonathan E. Rowe, Michael D. Vose, Alden H. Wright
BMCBI
2011
13 years 20 days ago
Motif-guided sparse decomposition of gene expression data for regulatory module identification
Background: Genes work coordinately as gene modules or gene networks. Various computational approaches have been proposed to find gene modules based on gene expression data; for e...
Ting Gong, Jianhua Xuan, Li Chen, Rebecca B. Riggi...
BMCBI
2007
114views more  BMCBI 2007»
13 years 5 months ago
Large scale statistical inference of signaling pathways from RNAi and microarray data
Background: The advent of RNA interference techniques enables the selective silencing of biologically interesting genes in an efficient way. In combination with DNA microarray tec...
Holger Fröhlich, Mark Fellmann, Holger Sü...