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BMCBI
2006
114views more  BMCBI 2006»
13 years 4 months ago
Empirical validation of the S-Score algorithm in the analysis of gene expression data
Background: Current methods of analyzing Affymetrix GeneChip
Richard E. Kennedy, Kellie J. Archer, Michael F. M...
BMCBI
2010
158views more  BMCBI 2010»
13 years 4 months ago
Validation of differential gene expression algorithms: Application comparing fold-change estimation to hypothesis testing
Background: Sustained research on the problem of determining which genes are differentially expressed on the basis of microarray data has yielded a plethora of statistical algorit...
Corey M. Yanofsky, David R. Bickel
BMCBI
2005
122views more  BMCBI 2005»
13 years 4 months ago
GenClust: A genetic algorithm for clustering gene expression data
Background: Clustering is a key step in the analysis of gene expression data, and in fact, many classical clustering algorithms are used, or more innovative ones have been designe...
Vito Di Gesù, Raffaele Giancarlo, Giosu&egr...
BMCBI
2006
101views more  BMCBI 2006»
13 years 4 months ago
SynTReN: a generator of synthetic gene expression data for design and analysis of structure learning algorithms
Background: The development of algorithms to infer the structure of gene regulatory networks based on expression data is an important subject in bioinformatics research. Validatio...
Tim Van den Bulcke, Koen Van Leemput, Bart Naudts,...
ITA
2006
167views Communications» more  ITA 2006»
13 years 4 months ago
Characterization of lung tumor subtypes through gene expression cluster validity assessment
The problem of assessing the reliability of clusters patients identified by clustering algorithms is crucial to estimate the significance of subclasses of diseases detectable at b...
Giorgio Valentini, Francesca Ruffino