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BMCBI
2011
12 years 12 months ago
Motif-guided sparse decomposition of gene expression data for regulatory module identification
Background: Genes work coordinately as gene modules or gene networks. Various computational approaches have been proposed to find gene modules based on gene expression data; for e...
Ting Gong, Jianhua Xuan, Li Chen, Rebecca B. Riggi...
BMCBI
2006
164views more  BMCBI 2006»
13 years 4 months ago
Evaluation of clustering algorithms for gene expression data
Background: Cluster analysis is an integral part of high dimensional data analysis. In the context of large scale gene expression data, a filtered set of genes are grouped togethe...
Susmita Datta, Somnath Datta
BMCBI
2007
128views more  BMCBI 2007»
13 years 4 months ago
Combining classifiers to predict gene function in Arabidopsis thaliana using large-scale gene expression measurements
Background: Arabidopsis thaliana is the model species of current plant genomic research with a genome size of 125 Mb and approximately 28,000 genes. The function of half of these ...
Hui Lan, Rachel Carson, Nicholas J. Provart, Antho...
KES
2008
Springer
13 years 4 months ago
An Algorithm to Assess the Reliability of Hierarchical Clusters in Gene Expression Data
The validation of clusters discovered in bio-molecular data is a central issue in bioinformatics. Recently, stability-based methods have been successfully applied to the analysis o...
Roberto Avogadri, Matteo Brioschi, Francesca Ruffi...
BMCBI
2008
178views more  BMCBI 2008»
13 years 5 months ago
Identification of coherent patterns in gene expression data using an efficient biclustering algorithm and parallel coordinate vi
Background: The DNA microarray technology allows the measurement of expression levels of thousands of genes under tens/hundreds of different conditions. In microarray data, genes ...
Kin-On Cheng, Ngai-Fong Law, Wan-Chi Siu, Alan Wee...