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CBMS
2009
IEEE
14 years 3 days ago
Enabling effective curation of cancer biomarker research data
The dramatic increase in data in the area of cancer research has elevated the importance of effectively managing the quality and consistency of research results from multiple prov...
Andrew F. Hart, Chris Mattmann, John J. Tran, Dani...
BMCBI
2010
146views more  BMCBI 2010»
13 years 5 months ago
Nonnegative principal component analysis for mass spectral serum profiles and biomarker discovery
Background: As a novel cancer diagnostic paradigm, mass spectroscopic serum proteomic pattern diagnostics was reported superior to the conventional serologic cancer biomarkers. Ho...
Henry Han
BMCBI
2007
217views more  BMCBI 2007»
13 years 5 months ago
On consensus biomarker selection
Background: Recent development of mass spectrometry technology enabled the analysis of complex peptide mixtures. A lot of effort is currently devoted to the identification of biom...
Janusz Dutkowski, Anna Gambin
BMCBI
2004
180views more  BMCBI 2004»
13 years 5 months ago
Noise filtering and nonparametric analysis of microarray data underscores discriminating markers of oral, prostate, lung, ovaria
Background: A major goal of cancer research is to identify discrete biomarkers that specifically characterize a given malignancy. These markers are useful in diagnosis, may identi...
Virginie M. Aris, Michael J. Cody, Jeff Cheng, Jam...
CBMS
2003
IEEE
13 years 10 months ago
A National Virtual Specimen Database for Early Cancer Detection
Access to biospecimens is essential for enabling cancer biomarker discovery. The National Cancer Institute's (NCI) Early Detection Research Network (EDRN) comprises and integ...
Heather Kincaid, Sean C. Kelly, Daniel J. Crichton...