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» Enabling proteomics-based identification of human cancer var...
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BMCBI
2010
82views more  BMCBI 2010»
13 years 5 months ago
Genome-wide estimation of firing efficiencies of origins of DNA replication from time-course copy number variation data
Background: DNA replication is a fundamental biological process during S phase of cell division. It is initiated from several hundreds of origins along whole chromosome with diffe...
Huaien Luo, Juntao Li, Majid Eshaghi, Jianhua Liu,...
BMCBI
2006
178views more  BMCBI 2006»
13 years 5 months ago
Correlation analysis of two-dimensional gel electrophoretic protein patterns and biological variables
Background: Two-dimensional gel electrophoresis (2DE) is a powerful technique to examine post-translational modifications of complexly modulated proteins. Currently, spot detectio...
Werner W. V. B. Van Belle, Nina N. A. Anensen, Ing...
BMCBI
2010
214views more  BMCBI 2010»
13 years 5 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper
BMCBI
2006
127views more  BMCBI 2006»
13 years 5 months ago
PathogenMIPer: a tool for the design of molecular inversion probes to detect multiple pathogens
Background: Here we describe PathogenMIPer, a software program for designing molecular inversion probe (MIP) oligonucleotides for use in pathogen identification and detection. The...
Sreedevi Thiyagarajan, Miloslav Karhanek, Michael ...
BMCBI
2007
217views more  BMCBI 2007»
13 years 5 months ago
On consensus biomarker selection
Background: Recent development of mass spectrometry technology enabled the analysis of complex peptide mixtures. A lot of effort is currently devoted to the identification of biom...
Janusz Dutkowski, Anna Gambin