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» Ensemble of Linear Models for Predicting Drug Properties
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BIOSYSTEMS
2008
107views more  BIOSYSTEMS 2008»
13 years 5 months ago
The linearity of emergent spectro-temporal receptive fields in a model of auditory cortex
The responses of cortical neurons are often characterized by measuring their spectro-temporal receptive fields (strfs). The strf of a cell can be thought of as a representation of...
Martin Coath, Emili Balaguer-Ballester, Sue L. Den...
JCC
2007
82views more  JCC 2007»
13 years 5 months ago
Peptide reagent design based on physical and chemical properties of amino acid residues
: It has tremendous values for both drug discovery and basic research to develop a solid bioinformatical tool for guiding peptide reagent design. Based on the physical and chemical...
Qishi Du, Ri-Bo Huang, Yu-Tuo Wei, Cheng-Hua Wang,...
KDD
2010
ACM
265views Data Mining» more  KDD 2010»
13 years 9 months ago
Combining predictions for accurate recommender systems
We analyze the application of ensemble learning to recommender systems on the Netflix Prize dataset. For our analysis we use a set of diverse state-of-the-art collaborative filt...
Michael Jahrer, Andreas Töscher, Robert Legen...
BMCBI
2008
92views more  BMCBI 2008»
13 years 5 months ago
Proteochemometric modeling of HIV protease susceptibility
Background: A major obstacle in treatment of HIV is the ability of the virus to mutate rapidly into drug-resistant variants. A method for predicting the susceptibility of mutated ...
Maris Lapinsh, Martin Eklund, Ola Spjuth, Peteris ...
BMCBI
2010
120views more  BMCBI 2010»
13 years 5 months ago
KiDoQ: using docking based energy scores to develop ligand based model for predicting antibacterials
Background: Identification of novel drug targets and their inhibitors is a major challenge in the field of drug designing and development. Diaminopimelic acid (DAP) pathway is a u...
Aarti Garg, Rupinder Tewari, Gajendra P. S. Raghav...