18 search results - page 3 / 4 » Epigenetic priors for identifying active transcription facto... |
BMCBI
2008
13 years 5 months ago
2008
Background: Cis-regulatory modules (CRMs) are distinct, genomic regions surrounding the target gene that can independently activate the promoter to drive transcription. The activa...
BMCBI
2010
13 years 5 months ago
2010
Background: Observed co-expression of a group of genes is frequently attributed to co-regulation by shared transcription factors. This assumption has led to the hypothesis that pr...
BMCBI
2007
13 years 5 months ago
2007
Background: Cell specific gene expression is largely regulated by different combinations of transcription factors that bind cis-elements in the upstream promoter sequence. However...
BMCBI
2011
13 years 23 days ago
2011
Background: With the advent of cost-effective genotyping technologies, genome-wide association studies allow researchers to examine hundreds of thousands of single nucleotide poly...
BMCBI
2005
13 years 5 months ago
2005
Background: The multitude of motif detection algorithms developed to date have largely focused on the detection of patterns in primary sequence. Since sequence-dependent DNA struc...