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GCB
2000
Springer
137views Biometrics» more  GCB 2000»
13 years 8 months ago
Detecting Sporadic Recombination in DNA Alignments with Hidden Markov Models
Conventional phylogenetic tree estimation methods assume that all sites in a DNA multiple alignment have the same evolutionary history. This assumption is violated in data sets fro...
Dirk Husmeier, Frank Wright
BMCBI
2008
103views more  BMCBI 2008»
13 years 5 months ago
Parameter estimation for robust HMM analysis of ChIP-chip data
Background: Tiling arrays are an important tool for the study of transcriptional activity, proteinDNA interactions and chromatin structure on a genome-wide scale at high resolutio...
Peter Humburg, David Bulger, Glenn Stone
BMCBI
2010
113views more  BMCBI 2010»
13 years 5 months ago
Unifying generative and discriminative learning principles
Background: The recognition of functional binding sites in genomic DNA remains one of the fundamental challenges of genome research. During the last decades, a plethora of differe...
Jens Keilwagen, Jan Grau, Stefan Posch, Marc Stric...
CRV
2009
IEEE
237views Robotics» more  CRV 2009»
13 years 12 months ago
SEC: Stochastic Ensemble Consensus Approach to Unsupervised SAR Sea-Ice Segmentation
The use of synthetic aperture radar (SAR) has become an integral part of sea-ice monitoring and analysis in the polar regions. An important task in sea-ice analysis is to segment ...
Alexander Wong, David A. Clausi, Paul W. Fieguth
BMCBI
2008
144views more  BMCBI 2008»
13 years 5 months ago
Local conservation scores without a priori assumptions on neutral substitution rates
Background: Comparative genomics aims to detect signals of evolutionary conservation as an indicator of functional constraint. Surprisingly, results of the ENCODE project revealed...
Janis Dingel, Pavol Hanus, Niccolò Leonardi...