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IDA
2009
Springer
13 years 1 months ago
Estimating Hidden Influences in Metabolic and Gene Regulatory Networks
We address the applicability of blind source separation (BSS) methods for the estimation of hidden influences in biological dynamic systems such as metabolic or gene regulatory net...
Florian Blöchl, Fabian J. Theis
BMCBI
2005
189views more  BMCBI 2005»
13 years 3 months ago
Quantitative inference of dynamic regulatory pathways via microarray data
Background: The cellular signaling pathway (network) is one of the main topics of organismic investigations. The intracellular interactions between genes in a signaling pathway ar...
Wen-Chieh Chang, Chang-Wei Li, Bor-Sen Chen
BMCBI
2008
121views more  BMCBI 2008»
13 years 3 months ago
ReAlignerV: Web-based genomic alignment tool with high specificity and robustness estimated by species-specific insertion sequen
Background: Detecting conserved noncoding sequences (CNSs) across species highlights the functional elements. Alignment procedures combined with computational prediction of transc...
Hisakazu Iwama, Yukio Hori, Kensuke Matsumoto, Koj...
BMCBI
2006
127views more  BMCBI 2006»
13 years 3 months ago
On the attenuation and amplification of molecular noise in genetic regulatory networks
Background: Noise has many important roles in cellular genetic regulatory functions at the nanomolar scale. At present, no good theory exists for identifying all possible mechanis...
Bor-Sen Chen, Yu-Chao Wang
JCP
2006
157views more  JCP 2006»
13 years 3 months ago
CF-GeNe: Fuzzy Framework for Robust Gene Regulatory Network Inference
Most Gene Regulatory Network (GRN) studies ignore the impact of the noisy nature of gene expression data despite its significant influence upon inferred results. This paper present...
Muhammad Shoaib B. Sehgal, Iqbal Gondal, Laurence ...