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» Estimating p-values in small microarray experiments
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BMCBI
2007
194views more  BMCBI 2007»
13 years 5 months ago
A meta-data based method for DNA microarray imputation
Background: DNA microarray experiments are conducted in logical sets, such as time course profiling after a treatment is applied to the samples, or comparisons of the samples unde...
Rebecka Jörnsten, Ming Ouyang, Hui-Yu Wang
BMCBI
2006
118views more  BMCBI 2006»
13 years 5 months ago
Microarray image analysis: background estimation using quantile and morphological filters
Background: In a microarray experiment the difference in expression between genes on the same slide is up to 103 fold or more. At low expression, even a small error in the estimat...
Anders Bengtsson, Henrik Bengtsson
BMCBI
2008
99views more  BMCBI 2008»
13 years 5 months ago
Ranking analysis of F-statistics for microarray data
Background: Microarray technology provides an efficient means for globally exploring physiological processes governed by the coordinated expression of multiple genes. However, ide...
Yuan-De Tan, Myriam Fornage, Hongyan Xu
BMCBI
2007
99views more  BMCBI 2007»
13 years 5 months ago
Stratification bias in low signal microarray studies
Background: When analysing microarray and other small sample size biological datasets, care is needed to avoid various biases. We analyse a form of bias, stratification bias, that...
Brian J. Parker, Simon Günter, Justin Bedo
BMCBI
2006
156views more  BMCBI 2006»
13 years 5 months ago
Bayesian models for pooling microarray studies with multiple sources of replications
Background: Biologists often conduct multiple but different cDNA microarray studies that all target the same biological system or pathway. Within each study, replicate slides with...
Erin M. Conlon, Joon J. Song, Jun S. Liu