31 search results - page 2 / 7 » Estimation of allele frequency and association mapping using... |
BMCBI
2011
12 years 8 months ago
2011
Background: Next generation ultra-sequencing technologies are starting to produce extensive quantities of data from entire human genome or exome sequences, and therefore new softw...
BMCBI
2010
13 years 5 months ago
2010
Background: Haplotype-based approaches have been extensively studied for case-control association mapping in recent years. It has been shown that haplotype methods can provide mor...
BMCBI
2010
13 years 5 months ago
2010
Background: Combining data from different ethnic populations in a study can increase efficacy of methods designed to identify expression quantitative trait loci (eQTL) compared to...
BMCBI
2008
13 years 5 months ago
2008
Background: Population structure analysis is important to genetic association studies and evolutionary investigations. Parametric approaches, e.g. STRUCTURE and L-POP, usually ass...
BMCBI
2008
13 years 5 months ago
2008
Background: Association testing is a powerful tool for identifying disease susceptibility genes underlying complex diseases. Technological advances have yielded a dramatic increas...