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BMCBI
2008
170views more  BMCBI 2008»
13 years 4 months ago
Evaluation of GO-based functional similarity measures using S. cerevisiae protein interaction and expression profile data
Background: Researchers interested in analysing the expression patterns of functionally related genes usually hope to improve the accuracy of their results beyond the boundaries o...
Tao Xu, LinFang Du, Yan Zhou
BMCBI
2008
158views more  BMCBI 2008»
13 years 4 months ago
Metrics for GO based protein semantic similarity: a systematic evaluation
Background: Several semantic similarity measures have been applied to gene products annotated with Gene Ontology terms, providing a basis for their functional comparison. However,...
Catia Pesquita, Daniel Faria, Hugo P. Bastos, Ant&...
BMCBI
2005
86views more  BMCBI 2005»
13 years 4 months ago
Confirmation of human protein interaction data by human expression data
Background: With microarray technology the expression of thousands of genes can be measured simultaneously. It is well known that the expression levels of genes of interacting pro...
Andreas Hahn, Jörg Rahnenführer, Priti T...
CSB
2005
IEEE
139views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Predicting gene function by combining expression and interaction data
In this study we combined the spurious protein interaction data from the Database of Interacting Proteins with the recently published gene expression data of S. cerevisiae grown w...
Rogier J. P. van Berlo, Lodewyk F. A. Wessels, S. ...
BIOINFORMATICS
2006
135views more  BIOINFORMATICS 2006»
13 years 4 months ago
Effective similarity measures for expression profiles
It is commonly accepted that genes with similar expression profiles are functionally related. However, there are many ways one can measure the similarity of expression profiles, a...
Golan Yona, William Dirks, Shafquat Rahman, David ...