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GCB
2000
Springer
137views Biometrics» more  GCB 2000»
13 years 9 months ago
Detecting Sporadic Recombination in DNA Alignments with Hidden Markov Models
Conventional phylogenetic tree estimation methods assume that all sites in a DNA multiple alignment have the same evolutionary history. This assumption is violated in data sets fro...
Dirk Husmeier, Frank Wright
IPPS
2003
IEEE
13 years 10 months ago
Phylogenetic Tree Inference on PC Architectures with AxML/PAxML
Inference of phylogenetic trees comprising hundreds or even thousands of organisms based on the maximum likelihood method is computationally extremely expensive. In previous work,...
Alexandros Stamatakis, Thomas Ludwig 0002
BMCBI
2005
134views more  BMCBI 2005»
13 years 5 months ago
Ancestral sequence alignment under optimal conditions
Background: Multiple genome alignment is an important problem in bioinformatics. An important subproblem used by many multiple alignment approaches is that of aligning two multipl...
Alexander K. Hudek, Daniel G. Brown 0001
BMCBI
2004
94views more  BMCBI 2004»
13 years 5 months ago
GASP: Gapped Ancestral Sequence Prediction for proteins
Background: The prediction of ancestral protein sequences from multiple sequence alignments is useful for many bioinformatics analyses. Predicting ancestral sequences is not a sim...
Richard J. Edwards, Denis C. Shields
BMCBI
2010
145views more  BMCBI 2010»
13 years 5 months ago
JCoDA: a tool for detecting evolutionary selection
Background: The incorporation of annotated sequence information from multiple related species in commonly used databases (Ensembl, Flybase, Saccharomyces Genome Database, Wormbase...
Steven N. Steinway, Ruth Dannenfelser, Christopher...