The toxicity of an anticancer drug is cleared from the body by different processes, including saturable metabolic and nonsaturable renal-excretion pathways. According to the princ...
This paper presents a modified optimal control model of drug scheduling in cancer chemotherapy and a new adaptive elitist-population based genetic algorithm (AEGA) to solve it. Wo...
In this paper, we investigate the employment of evolutionary algorithms as a search mechanism in a decision support system for designing chemotherapy schedules. Chemotherapy invol...
Abstract-- Cancer treatment by chemotherapy involves multiple applications of toxic drugs over a period of time. Optimising the schedule of these treatments can improve the outcome...
In this paper, derivation of the optimal chemotherapy schedule is formulated and solved as a dynamic optimization problem. For this purpose two models representing the tumour grow...