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» Evolutionary Tuning of Combined Multiple Models
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BMCBI
2005
122views more  BMCBI 2005»
13 years 6 months ago
Bayesian coestimation of phylogeny and sequence alignment
Background: Two central problems in computational biology are the determination of the alignment and phylogeny of a set of biological sequences. The traditional approach to this p...
Gerton Lunter, István Miklós, Alexei...
JMLR
2012
11 years 8 months ago
Bayesian regularization of non-homogeneous dynamic Bayesian networks by globally coupling interaction parameters
To relax the homogeneity assumption of classical dynamic Bayesian networks (DBNs), various recent studies have combined DBNs with multiple changepoint processes. The underlying as...
Marco Grzegorczyk, Dirk Husmeier
BMCBI
2004
158views more  BMCBI 2004»
13 years 6 months ago
Improvement of alignment accuracy utilizing sequentially conserved motifs
Background: Multiple sequence alignment algorithms are very important tools in molecular biology today. Accurate alignment of proteins is central to several areas such as homology...
Saikat Chakrabarti, Nitin Bhardwaj, Prem A. Anand,...
BMCBI
2010
177views more  BMCBI 2010»
13 years 6 months ago
Clustering of protein families into functional subtypes using Relative Complexity Measure with reduced amino acid alphabets
Background: Phylogenetic analysis can be used to divide a protein family into subfamilies in the absence of experimental information. Most phylogenetic analysis methods utilize mu...
Aydin Albayrak, Hasan H. Otu, Ugur O. Sezerman
EPS
1998
Springer
13 years 10 months ago
Acquisition of General Adaptive Features by Evolution
We investigate the following question. Do populations of evolving agents adapt only to their recent environment or do general adaptive features appear over time? We find statistica...
Dan Ashlock, John E. Mayfield