In this paper we propose new solution methods for designing tag sets for use in universal DNA arrays. First, we give integer linear programming formulations for two previous formal...
Sets of DNA strands that satisfy combinatorial constraints play an important role in various approaches to biomolecular computation, nanostructure design, and molecular tagging. Th...
Background: Molecular biologists work with DNA databases that often include entire genomes. A common requirement is to search a DNA database to find exact matches for a nondegener...
In this paper, we investigate the test set problem and its variations that appear in a variety of applications. In general, we are given a universe of objects to be “distinguish...
Background: Serial Analysis of Gene Expression (SAGE) is a high-throughput method for inferring mRNA expression levels from the experimentally generated sequence based tags. Stand...
Michael A. Gilchrist, Hong Qin, Russell L. Zaretzk...