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» Exact and Approximation Algorithms for DNA Tag Set Design
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CPM
2005
Springer
116views Combinatorics» more  CPM 2005»
13 years 10 months ago
Exact and Approximation Algorithms for DNA Tag Set Design
In this paper we propose new solution methods for designing tag sets for use in universal DNA arrays. First, we give integer linear programming formulations for two previous formal...
Ion I. Mandoiu, Dragos Trinca
AI
2003
Springer
13 years 9 months ago
Hybrid Randomised Neighbourhoods Improve Stochastic Local Search for DNA Code Design
Sets of DNA strands that satisfy combinatorial constraints play an important role in various approaches to biomolecular computation, nanostructure design, and molecular tagging. Th...
Dan C. Tulpan, Holger H. Hoos
BMCBI
2006
116views more  BMCBI 2006»
13 years 4 months ago
MICA: desktop software for comprehensive searching of DNA databases
Background: Molecular biologists work with DNA databases that often include entire genomes. A common requirement is to search a DNA database to find exact matches for a nondegener...
William A. Stokes, Benjamin S. Glick
SWAT
2004
Springer
98views Algorithms» more  SWAT 2004»
13 years 9 months ago
Tight Approximability Results for Test Set Problems in Bioinformatics
In this paper, we investigate the test set problem and its variations that appear in a variety of applications. In general, we are given a universe of objects to be “distinguish...
Piotr Berman, Bhaskar DasGupta, Ming-Yang Kao
BMCBI
2007
106views more  BMCBI 2007»
13 years 4 months ago
Modeling SAGE tag formation and its effects on data interpretation within a Bayesian framework
Background: Serial Analysis of Gene Expression (SAGE) is a high-throughput method for inferring mRNA expression levels from the experimentally generated sequence based tags. Stand...
Michael A. Gilchrist, Hong Qin, Russell L. Zaretzk...