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» Exploring a Two-Population Genetic Algorithm
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BMCBI
2007
161views more  BMCBI 2007»
13 years 5 months ago
Efficient classification of complete parameter regions based on semidefinite programming
Background: Current approaches to parameter estimation are often inappropriate or inconvenient for the modelling of complex biological systems. For systems described by nonlinear ...
Lars Kuepfer, Uwe Sauer, Pablo A. Parrilo
BMCBI
2006
175views more  BMCBI 2006»
13 years 5 months ago
Parameter estimation for stiff equations of biosystems using radial basis function networks
Background: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for par...
Yoshiya Matsubara, Shinichi Kikuchi, Masahiro Sugi...
BMCBI
2005
189views more  BMCBI 2005»
13 years 5 months ago
Quantitative inference of dynamic regulatory pathways via microarray data
Background: The cellular signaling pathway (network) is one of the main topics of organismic investigations. The intracellular interactions between genes in a signaling pathway ar...
Wen-Chieh Chang, Chang-Wei Li, Bor-Sen Chen
APIN
1998
132views more  APIN 1998»
13 years 4 months ago
Evolution-Based Methods for Selecting Point Data for Object Localization: Applications to Computer-Assisted Surgery
Object localization has applications in many areas of engineering and science. The goal is to spatially locate an arbitrarily-shaped object. In many applications, it is desirable ...
Shumeet Baluja, David Simon
BMCBI
2007
131views more  BMCBI 2007»
13 years 5 months ago
ISHAPE: new rapid and accurate software for haplotyping
Background: We have developed a new haplotyping program based on the combination of an iterative multiallelic EM algorithm (IEM), bootstrap resampling and a pseudo Gibbs sampler. ...
Olivier Delaneau, Cédric Coulonges, Pierre-...