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ICPR
2008
IEEE
13 years 11 months ago
Gene function prediction using protein domain probability and hierarchical Gene Ontology information
The Gene Ontology (GO) is a controlled vocabulary of terms to describe protein functions. It also includes a hierarchical description of the relationships among the terms in the f...
Jaehee Jung, Michael R. Thon
BMCBI
2005
125views more  BMCBI 2005»
13 years 4 months ago
Query3d: a new method for high-throughput analysis of functional residues in protein structures
Background: The identification of local similarities between two protein structures can provide clues of a common function. Many different methods exist for searching for similar ...
Gabriele Ausiello, Allegra Via, Manuela Helmer-Cit...
BMCBI
2010
129views more  BMCBI 2010»
13 years 4 months ago
Detection of distant evolutionary relationships between protein families using theory of sequence profile-profile comparison
Background: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represent...
Mindaugas Margelevicius, Ceslovas Venclovas
BMCBI
2004
140views more  BMCBI 2004»
13 years 4 months ago
What can we learn from noncoding regions of similarity between genomes?
Background: In addition to known protein-coding genes, large amounts of apparently non-coding sequence are conserved between the human and mouse genomes. It seems reasonable to as...
Thomas A. Down, Tim J. P. Hubbard
BMCBI
2008
141views more  BMCBI 2008»
13 years 4 months ago
Functional discrimination of membrane proteins using machine learning techniques
Background: Discriminating membrane proteins based on their functions is an important task in genome annotation. In this work, we have analyzed the characteristic features of amin...
M. Michael Gromiha, Yukimitsu Yabuki