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» FISH - family identification of sequence homologues using st...
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ALMOB
2006
155views more  ALMOB 2006»
9 years 9 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
BMCBI
2010
99views more  BMCBI 2010»
9 years 9 months ago
Prediction of novel precursor miRNAs using a context-sensitive hidden Markov model (CSHMM)
Background: It has been apparent in the last few years that small non coding RNAs (ncRNA) play a very significant role in biological regulation. Among these microRNAs (miRNAs), 22...
Sumeet Agarwal, Candida Vaz, Alok Bhattacharya, As...
BMCBI
2010
229views more  BMCBI 2010»
9 years 9 months ago
Mocapy++ - A toolkit for inference and learning in dynamic Bayesian networks
Background: Mocapy++ is a toolkit for parameter learning and inference in dynamic Bayesian networks (DBNs). It supports a wide range of DBN architectures and probability distribut...
Martin Paluszewski, Thomas Hamelryck
BMCBI
2004
111views more  BMCBI 2004»
9 years 9 months ago
The Hotdog fold: wrapping up a superfamily of thioesterases and dehydratases
Background: The Hotdog fold was initially identified in the structure of Escherichia coli FabA and subsequently in 4-hydroxybenzoyl-CoA thioesterase from Pseudomonas sp. strain CB...
Shane C. Dillon, Alex Bateman
BIOINFORMATICS
2016
136views more  BIOINFORMATICS 2016»
4 years 5 months ago
De novo identification of replication-timing domains in the human genome by deep learning
Motivation: The de novo identiļ¬cation of the initiation and termination zonesā€”regions that replicate earlier or later than their upstream and downstream neighbours, respective...
Feng Liu, Chao Ren, Hao Li, Pingkun Zhou, Xiaochen...
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