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» Family specific rates of protein evolution
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BMCBI
2007
137views more  BMCBI 2007»
13 years 5 months ago
PlnTFDB: an integrative plant transcription factor database
Background: Transcription factors (TFs) are key regulatory proteins that enhance or repress the transcriptional rate of their target genes by binding to specific promoter regions ...
Diego Mauricio Riaño-Pachón, Sloboda...
BMCBI
2008
114views more  BMCBI 2008»
13 years 5 months ago
WSPMaker: a web tool for calculating selection pressure in proteins and domains using window-sliding
Background: In the study of adaptive evolution, it is important to detect the protein coding sites where natural selection is acting. In general, the ratio of the rate of non-syno...
Yong Seok Lee, Tae-Hyung Kim, Tae-Wook Kang, Won-H...
BMCBI
2011
12 years 9 months ago
Detection of Lineage-Specific Evolutionary Changes among Primate Species
Background: Comparison of the human genome with other primates offers the opportunity to detect evolutionary events that created the diverse phenotypes among the primate species. ...
Mihaela Pertea, Geo Pertea, Steven L. Salzberg
BMCBI
2002
101views more  BMCBI 2002»
13 years 5 months ago
Total sequence decomposition distinguishes functional modules, "molegos" in apurinic/apyrimidinic endonucleases
Background: Total sequence decomposition, using the web-based MASIA tool, identifies areas of conservation in aligned protein sequences. By structurally annotating these motifs, t...
Catherine H. Schein, Numan Özgün, Tadahi...
IMSCCS
2007
IEEE
14 years 2 days ago
Evolutionary Conservation of DNA-Contact residues in DNA-binding Domains
Background: DNA-binding proteins are of utmost importance to gene regulation. The identification of DNA-binding domains is useful for understanding the regulation mechanisms of DN...
Yao-Lin Chang, Huai-Kuang Tsai, Cheng-Yan Kao, Yun...