Background: Motif discovery aims to detect short, highly conserved patterns in a collection of unaligned DNA or protein sequences. Discriminative motif finding algorithms aim to i...
Background: The structure of many eukaryotic cell regulatory proteins is highly modular. They are assembled from globular domains, segments of natively disordered polypeptides and...
Claudia Chica, Alberto Labarga, Cathryn M. Gould, ...
A method is described for identification and classification of proteins encoded in large DNA sequences. Previously, an automated system was introduced for the general detection of...
PRINTS is a database of protein family ‘fingerprints’ offering a diagnostic resource for newly-determined sequences. By contrast with PROSITE, which uses single consensus expr...
Terri K. Attwood, Michael E. Beck, Darren R. Flowe...
: In biological sequence analysis, position specific scoring matrices (PSSMs) are widely used to represent sequence motifs. In this paper, we present a new nonheuristic algorithm, ...
Michael Beckstette, Dirk Strothmann, Robert Homann...