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BMCBI
2006
145views more  BMCBI 2006»
9 years 11 months ago
Fast-Find: A novel computational approach to analyzing combinatorial motifs
Background: Many vital biological processes, including transcription and splicing, require a combination of short, degenerate sequence patterns, or motifs, adjacent to defined seq...
Micah Hamady, Erin Peden, Rob Knight, Ravinder Sin...
ALMOB
2006
138views more  ALMOB 2006»
9 years 11 months ago
A combinatorial optimization approach for diverse motif finding applications
Background: Discovering approximately repeated patterns, or motifs, in biological sequences is an important and widely-studied problem in computational molecular biology. Most fre...
Elena Zaslavsky, Mona Singh
IMSCCS
2006
IEEE
10 years 5 months ago
Combining Comparative Genomics with de novo Motif Discovery to Identify Human Transcription Factor DNA-Binding Motifs
Background: As more and more genomes are sequenced, comparative genomics approaches provide a methodology for identifying conserved regulatory elements that may be involved in gen...
Linyong Mao, W. Jim Zheng
CCE
2006
9 years 11 months ago
New approaches for representing, analyzing and visualizing complex kinetic transformations
Complex kinetic mechanisms involving thousands of reacting species and tens of thousands of reactions are currently required for the rational analysis of modern combustion systems...
Ioannis P. Androulakis
BMCBI
2005
201views more  BMCBI 2005»
9 years 11 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
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