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BMCBI
2011
12 years 8 months ago
Biomarker Discovery and Redundancy Reduction towards Classification using a Multi-factorial MALDI-TOF MS T2DM Mouse Model Datase
Background: Diabetes like many diseases and biological processes is not mono-causal. On the one hand multifactorial studies with complex experimental design are required for its c...
Chris Bauer, Frank Kleinjung, Celia J. Smith, Mark...
ALMOB
2006
135views more  ALMOB 2006»
13 years 4 months ago
P-value based visualization of codon usage data
Two important and not yet solved problems in bacterial genome research are the identification of horizontally transferred genes and the prediction of gene expression levels. Both ...
Peter Meinicke, Thomas Brodag, Wolfgang Florian Fr...
ICML
2010
IEEE
13 years 5 months ago
From Transformation-Based Dimensionality Reduction to Feature Selection
Many learning applications are characterized by high dimensions. Usually not all of these dimensions are relevant and some are redundant. There are two main approaches to reduce d...
Mahdokht Masaeli, Glenn Fung, Jennifer G. Dy
BMCBI
2006
142views more  BMCBI 2006»
13 years 4 months ago
Improving the Performance of SVM-RFE to Select Genes in Microarray Data
Background: Recursive Feature Elimination is a common and well-studied method for reducing the number of attributes used for further analysis or development of prediction models. ...
Yuanyuan Ding, Dawn Wilkins
BMCBI
2005
190views more  BMCBI 2005»
13 years 4 months ago
An Entropy-based gene selection method for cancer classification using microarray data
Background: Accurate diagnosis of cancer subtypes remains a challenging problem. Building classifiers based on gene expression data is a promising approach; yet the selection of n...
Xiaoxing Liu, Arun Krishnan, Adrian Mondry