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BMCBI
2006
119views more  BMCBI 2006»
13 years 5 months ago
Utilization of two sample t-test statistics from redundant probe sets to evaluate different probe set algorithms in GeneChip stu
Background: The choice of probe set algorithms for expression summary in a GeneChip study has a great impact on subsequent gene expression data analysis. Spiked-in cRNAs with know...
Zihua Hu, Gail R. Willsky
BMCBI
2004
120views more  BMCBI 2004»
13 years 5 months ago
Optimal cDNA microarray design using expressed sequence tags for organisms with limited genomic information
Background: Expression microarrays are increasingly used to characterize environmental responses and hostparasite interactions for many different organisms. Probe selection for cD...
Yian A. Chen, David J. Mckillen, Shuyuan Wu, Matth...
ISNN
2007
Springer
13 years 11 months ago
Memetic Algorithms for Feature Selection on Microarray Data
In this paper, we present two novel memetic algorithms (MAs) for gene selection. Both are synergies of Genetic Algorithm (wrapper methods) and local search methods (filter methods...
Zexuan Zhu, Yew-Soon Ong
BMCBI
2008
163views more  BMCBI 2008»
13 years 5 months ago
Gene Ontology term overlap as a measure of gene functional similarity
Background: The availability of various high-throughput experimental and computational methods allows biologists to rapidly infer functional relationships between genes. It is oft...
Meeta Mistry, Paul Pavlidis
GECCO
2008
Springer
158views Optimization» more  GECCO 2008»
13 years 6 months ago
Objective reduction using a feature selection technique
This paper introduces two new algorithms to reduce the number of objectives in a multiobjective problem by identifying the most conflicting objectives. The proposed algorithms ar...
Antonio López Jaimes, Carlos A. Coello Coel...