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CIBCB
2005
IEEE
13 years 10 months ago
Feedback Memetic Algorithms for Modeling Gene Regulatory Networks
— In this paper we address the problem of finding gene regulatory networks from experimental DNA microarray data. We focus on the evaluation of the performance of memetic algori...
Christian Spieth, Felix Streichert, Jochen Supper,...
BMCBI
2007
186views more  BMCBI 2007»
13 years 4 months ago
Modeling human cancer-related regulatory modules by GA-RNN hybrid algorithms
Background: Modeling cancer-related regulatory modules from gene expression profiling of cancer tissues is expected to contribute to our understanding of cancer biology as well as...
Jung-Hsien Chiang, Shih-Yi Chao
BIOSYSTEMS
2007
111views more  BIOSYSTEMS 2007»
13 years 4 months ago
A Markovian approach to the control of genetic regulatory networks
This paper presents an approach for controlling gene networks based on a Markov chain model, where the state of a gene network is represented as a probability distribution, while ...
Peter C. Y. Chen, Jeremy W. Chen
CMSB
2006
Springer
13 years 8 months ago
Randomization and Feedback Properties of Directed Graphs Inspired by Gene Networks
Having in mind the large-scale analysis of gene regulatory networks, we review a graph decimation algorithm, called "leaf-removal", which can be used to evaluate the feed...
M. Cosentino Lagomarsino, P. Jona, B. Bassetti
BMCBI
2006
126views more  BMCBI 2006»
13 years 4 months ago
A joint model of regulatory and metabolic networks
Background: Gene regulation and metabolic reactions are two primary activities of life. Although many works have been dedicated to study each system, the coupling between them is ...
Chen-Hsiang Yeang, Martin Vingron