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TCBB
2008
103views more  TCBB 2008»
11 years 11 months ago
DNA Motif Representation with Nucleotide Dependency
The problem of discovering novel motifs of binding sites is important to the understanding of gene regulatory networks. Motifs are generally represented by matrices (PWM or PSSM) o...
Francis Y. L. Chin, Henry C. M. Leung
BMCBI
2007
127views more  BMCBI 2007»
11 years 11 months ago
Characterization and simulation of cDNA microarray spots using a novel mathematical model
Background: The quality of cDNA microarray data is crucial for expanding its application to other research areas, such as the study of gene regulatory networks. Despite the fact t...
Hye Young Kim, Seo Eun Lee, Min Jung Kim, Jin Il H...
SIAMSC
2008
149views more  SIAMSC 2008»
11 years 11 months ago
Adaptive Discrete Galerkin Methods Applied to the Chemical Master Equation
In systems biology, the stochastic description of biochemical reaction kinetics is increasingly being employed to model gene regulatory networks and signalling pathways. Mathematic...
Peter Deuflhard, Wilhelm Huisinga, T. Jahnke, Mich...
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