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» Flexible Stochastic Local Search for Haplotype Inference
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LION
2009
Springer
115views Optimization» more  LION 2009»
13 years 10 months ago
Flexible Stochastic Local Search for Haplotype Inference
Abstract. Haplotype Inference is a challenging problem in bioinformatics that consists in inferring the basic genetic constitution of diploid organisms on the basis of their genoty...
Luca Di Gaspero, Andrea Roli
CONSTRAINTS
2008
78views more  CONSTRAINTS 2008»
13 years 3 months ago
Boosting Haplotype Inference with Local Search
Abstract. A very challenging problem in the genetics domain is to infer haplotypes from genotypes. This process is expected to identify genes affecting health, disease and response...
Inês Lynce, João Marques-Silva, Steve...
HIS
2008
13 years 5 months ago
Towards a Highly Scalable Hybrid Metaheuristic for Haplotype Inference Under Parsimony
Haplotype Inference is a challenging problem in bioinformatics that consists in inferring the basic genetic constitution of diploid organisms on the basis of their genotype. This ...
Stefano Benedettini, Luca Di Gaspero, Andrea Roli
BMCBI
2006
135views more  BMCBI 2006»
13 years 3 months ago
iHAP - integrated haplotype analysis pipeline for characterizing the haplotype structure of genes
Background: The advent of genotype data from large-scale efforts that catalog the genetic variants of different populations have given rise to new avenues for multifactorial disea...
Chun Meng Song, Boon Huat Yeo, Erwin Tantoso, Yuch...
JCB
2008
159views more  JCB 2008»
13 years 3 months ago
BayesMD: Flexible Biological Modeling for Motif Discovery
We present BayesMD, a Bayesian Motif Discovery model with several new features. Three different types of biological a priori knowledge are built into the framework in a modular fa...
Man-Hung Eric Tang, Anders Krogh, Ole Winther