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BMCBI
2008
159views more  BMCBI 2008»
13 years 5 months ago
Estimation and testing for the effect of a genetic pathway on a disease outcome using logistic kernel machine regression via log
Background: Growing interest on biological pathways has called for new statistical methods for modeling and testing a genetic pathway effect on a health outcome. The fact that gen...
Dawei Liu, Debashis Ghosh, Xihong Lin
BMCBI
2006
115views more  BMCBI 2006»
13 years 5 months ago
Multivariate curve resolution of time course microarray data
Background: Modeling of gene expression data from time course experiments often involves the use of linear models such as those obtained from principal component analysis (PCA), i...
Peter D. Wentzell, Tobias K. Karakach, Sushmita Ro...
IJCAI
1989
13 years 6 months ago
A Model for Projection and Action
In designing autonomous agents that deal competently with issues involving time and space, there is a tradeoff to be made between guaranteed response-time reactions on the one han...
Keiji Kanazawa, Thomas Dean
BMCBI
2007
123views more  BMCBI 2007»
13 years 5 months ago
Heritable clustering and pathway discovery in breast cancer integrating epigenetic and phenotypic data
Background: In order to recapitulate tumor progression pathways using epigenetic data, we developed novel clustering and pathway reconstruction algorithms, collectively referred t...
Zailong Wang, Pearlly Yan, Dustin P. Potter, Chari...