5 search results - page 1 / 1 » Forward-time simulation of realistic samples for genome-wide... |
BMCBI
2010
13 years 5 months ago
2010
Background: Forward-time simulations have unique advantages in power and flexibility for the simulation of genetic samples of complex human diseases because they can closely mimic...
BMCBI
2008
13 years 5 months ago
2008
Background: FREGENE simulates sequence-level data over large genomic regions in large populations. Because, unlike coalescent simulators, it works forwards through time, it allows...
BMCBI
2007
13 years 4 months ago
2007
Background: Reverse engineering cellular networks is currently one of the most challenging problems in systems biology. Dynamic Bayesian networks (DBNs) seem to be particularly su...
BMCBI
2010
13 years 5 months ago
2010
Background: Copy number variations (CNVs) and polymorphisms (CNPs) have only recently gained the genetic community's attention. Conservative estimates have shown that CNVs an...
BMCBI
2010
13 years 5 months ago
2010
Background: Haplotype-based approaches have been extensively studied for case-control association mapping in recent years. It has been shown that haplotype methods can provide mor...