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BMCBI
2010
124views more  BMCBI 2010»
13 years 5 months ago
Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: Transcriptional dynamics and regu
Background: Comprehensively understanding corticosteroid pharmacogenomic effects is an essential step towards an insight into the underlying molecular mechanisms for both benefici...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
BMCBI
2006
120views more  BMCBI 2006»
13 years 5 months ago
The Virtual Insect Brain protocol: creating and comparing standardized neuroanatomy
Background: In the fly Drosophila melanogaster, new genetic, physiological, molecular and behavioral techniques for the functional analysis of the brain are rapidly accumulating. ...
Arnim Jenett, Johannes E. Schindelin, Martin Heise...
BMCBI
2004
150views more  BMCBI 2004»
13 years 5 months ago
Graph-based iterative Group Analysis enhances microarray interpretation
Background: One of the most time-consuming tasks after performing a gene expression experiment is the biological interpretation of the results by identifying physiologically impor...
Rainer Breitling, Anna Amtmann, Pawel Herzyk
BMCBI
2008
144views more  BMCBI 2008»
13 years 5 months ago
WGCNA: an R package for weighted correlation network analysis
Background: Correlation networks are increasingly being used in bioinformatics applications. For example, weighted gene co-expression network analysis is a systems biology method ...
Peter Langfelder, Steve Horvath
BMCBI
2007
141views more  BMCBI 2007»
13 years 5 months ago
HeliCis: a DNA motif discovery tool for colocalized motif pairs with periodic spacing
Background: Correct temporal and spatial gene expression during metazoan development relies on combinatorial interactions between different transcription factors. As a consequence...
Erik Larsson, Per Lindahl, Petter Mostad