Background: The function of a novel gene product is typically predicted by transitive assignment of annotation from similar sequences. We describe a novel method, GOtcha, for pred...
David M. A. Martin, Matthew Berriman, Geoffrey J. ...
The typical mode for querying in an image content-based information system is query-by-example, which allows the user to provide an image as a query and to search for similar imag...
PALS db is a collection of Putative Alternative Splicing information from 19 936 human UniGene clusters and 16 615 mouse UniGene clusters. Alternative splicing (AS) sites were pre...
Background: By virtue of their shared ancestry, homologous sequences are similar in their structure and function. Consequently, multiple sequence alignments are routinely used to ...
Daniel R. Caffrey, Paul H. Dana, Vidhya Mathur, Ma...
Abstract— We present a unifying framework for continuous optimization and sampling. This framework is based on Gaussian Adaptation (GaA), a search heuristic developed in the late...