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BMCBI
2007
159views more  BMCBI 2007»
13 years 5 months ago
sIR: siRNA Information Resource, a web-based tool for siRNA sequence design and analysis and an open access siRNA database
Background: RNA interference has revolutionized our ability to study the effects of altering the expression of single genes in mammalian (and other) cells through targeted knockdo...
Jyoti K. Shah, Harold R. Garner, Michael A. White,...
BMCBI
2008
129views more  BMCBI 2008»
13 years 5 months ago
Motif-directed network component analysis for regulatory network inference
Background: Network Component Analysis (NCA) has shown its effectiveness in discovering regulators and inferring transcription factor activities (TFAs) when both microarray data a...
Chen Wang, Jianhua Xuan, Li Chen, Po Zhao, Yue Wan...
BMCBI
2007
168views more  BMCBI 2007»
13 years 5 months ago
Advancing translational research with the Semantic Web
Background: A fundamental goal of the U.S. National Institute of Health (NIH) "Roadmap" is to strengthen Translational Research, defined as the movement of discoveries i...
Alan Ruttenberg, Tim Clark, William Bug, Matthias ...
NAR
2000
182views more  NAR 2000»
13 years 5 months ago
tmRDB (tmRNA database)
Maintained at the University of Texas Health Science Center at Tyler, Texas, the tmRNA database (tmRDB) is accessible at the URL http://psyche.uthct.edu/dbs/ tmRDB/tmRDB.html with...
Christian Zwieb, Jacek Wower
BMCBI
2008
116views more  BMCBI 2008»
13 years 5 months ago
Algorithm of OMA for large-scale orthology inference
Since the publication of our article (Roth, Gonnet, and Dessimoz: BMC Bioinformatics 2008 9: 518), we have noticed several errors, which we correct in the following. Correction We...
Alexander C. J. Roth, Gaston H. Gonnet, Christophe...