13 search results - page 1 / 3 » Functional annotation by identification of local surface sim... |
BMCBI
2005
13 years 4 months ago
2005
Background: Protein function is often dependent on subsets of solvent-exposed residues that may exist in a similar three-dimensional configuration in non homologous proteins thus ...
BMCBI
2008
13 years 4 months ago
2008
Background: Data mining in large DNA sequences is a major challenge in microbial genomics and bioinformatics. Oligonucleotide usage (OU) patterns provide a wealth of information f...
BMCBI
2007
13 years 4 months ago
2007
Background: Accurate identification of novel, functional noncoding (nc) RNA features in genome sequence has proven more difficult than for exons. Current algorithms identify and s...
BMCBI
2004
13 years 4 months ago
2004
Background: The function of a novel gene product is typically predicted by transitive assignment of annotation from similar sequences. We describe a novel method, GOtcha, for pred...
BMCBI
2006
13 years 4 months ago
2006
Background: With the completion of the genome sequences of human, mouse, and other species and the advent of high throughput functional genomic research technologies such as biomi...