Background: The knowledge about proteins with specific interaction capacity to the protein partners is very important for the modeling of cell signaling networks. However, the exp...
Boris Sobolev, Dmitry Filimonov, Alexey Lagunin, A...
Background: Prediction of protein localization in subnuclear organelles is more challenging than general protein subcelluar localization. There are only three computational models...
Background: Predicting the three-dimensional structure of a protein from its amino acid sequence is a long-standing goal in computational/molecular biology. The discrimination of ...
Background: Protein kinases play crucial roles in cell growth, differentiation, and apoptosis. Abnormal function of protein kinases can lead to many serious diseases, such as canc...
— The ability to identify protein binding sites and to detect specific amino acid residues that contribute to the specificity and affinity of protein interactions has importan...