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    » Functional coherence in domain interaction networks
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    BMCBI
    2008
    123views more  BMCBI 2008»
    Functional module detection by functional flow pattern mining in protein interaction networks
    13 years 5 months ago
    Functional module detection by functional flow pattern mining in protein interaction networks
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    eraction networks. In this abstract, we extend this approach by mining functional flow patterns for the purpose of detecting small-sized modules for specific functions. Methods Our...
    Young-Rae Cho, Lei Shi, Aidong Zhang
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    BMCBI
    2010
    122views more  BMCBI 2010»
    Functional enrichment analyses and construction of functional similarity networks with high confidence function prediction by PF
    13 years 10 days ago
    Functional enrichment analyses and construction of functional similarity networks with high confidence function prediction by PF
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    Background: A new paradigm of biological investigation takes advantage of technologies that produce large high throughput datasets, including genome sequences, interactions of pro...
    Troy Hawkins, Meghana Chitale, Daisuke Kihara
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    BMCBI
    2007
    227views more  BMCBI 2007»
    Growing functional modules from a seed protein via integration of protein interaction and gene expression data
    13 years 5 months ago
    Growing functional modules from a seed protein via integration of protein interaction and gene expression data
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    Background: Nowadays modern biology aims at unravelling the strands of complex biological structures such as the protein-protein interaction (PPI) networks. A key concept in the o...
    Ioannis A. Maraziotis, Konstantina Dimitrakopoulou...
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    GCB
    2007
    Springer
    161views Biometrics» more  GCB 2007»
    High-Precision Function Prediction using Conserved Interactions
    13 years 11 months ago
    High-Precision Function Prediction using Conserved Interactions
    Download  www.informatik.hu-berlin.de
    : The recent availability of large data sets of protein- protein-interactions (PPIs) from various species offers new opportunities for functional genomics and proteomics. We descri...
    Samira Jaeger, Ulf Leser
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    BMCBI
    2007
    107views more  BMCBI 2007»
    Reuse of structural domain-domain interactions in protein networks
    13 years 5 months ago
    Reuse of structural domain-domain interactions in protein networks
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    Background: Protein interactions are thought to be largely mediated by interactions between structural domains. Databases such as iPfam relate interactions in protein structures t...
    Benjamin Schuster-Böckler, Alex Bateman
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