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» Functional discrimination of membrane proteins using machine...
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BMCBI
2006
100views more  BMCBI 2006»
13 years 5 months ago
STAR: predicting recombination sites from amino acid sequence
Background: Designing novel proteins with site-directed recombination has enormous prospects. By locating effective recombination sites for swapping sequence parts, the probabilit...
Denis C. Bauer, Mikael Bodén, Ricarda Thier...
ICML
2007
IEEE
14 years 6 months ago
Classifying matrices with a spectral regularization
We propose a method for the classification of matrices. We use a linear classifier with a novel regularization scheme based on the spectral 1-norm of its coefficient matrix. The s...
Ryota Tomioka, Kazuyuki Aihara
BMCBI
2005
189views more  BMCBI 2005»
13 years 5 months ago
A sentence sliding window approach to extract protein annotations from biomedical articles
Background: Within the emerging field of text mining and statistical natural language processing (NLP) applied to biomedical articles, a broad variety of techniques have been deve...
Martin Krallinger, Maria Padron, Alfonso Valencia
BMCBI
2006
112views more  BMCBI 2006»
13 years 5 months ago
Protein disorder prediction by condensed PSSM considering propensity for order or disorder
Background: More and more disordered regions have been discovered in protein sequences, and many of them are found to be functionally significant. Previous studies reveal that dis...
Chung-Tsai Su, Chien-Yu Chen, Yu-Yen Ou
BMCBI
2008
143views more  BMCBI 2008»
13 years 5 months ago
Automatic detection of exonic splicing enhancers (ESEs) using SVMs
Background: Exonic splicing enhancers (ESEs) activate nearby splice sites and promote the inclusion (vs. exclusion) of exons in which they reside, while being a binding site for S...
Britta Mersch, Alexander Gepperth, Sándor S...