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BCB
2010
126views Bioinformatics» more  BCB 2010»
12 years 11 months ago
Functional similarities of reaction sets in metabolic pathways
Analyzing metabolic pathways by means of their steady states has proven to be accurate and efficient for practical purposes. The models such as elementary flux modes (EFMs) and ex...
Ferhat Ay, Tamer Kahveci
GG
2004
Springer
13 years 9 months ago
Analysis of Metabolic Pathways by Graph Transformation
Biochemical pathways, such as metabolic, regulatory, and signal transduction pathways, constitute complex networks of functional and physical interactions between molecular species...
Francesc Rosselló, Gabriel Valiente
IV
2008
IEEE
296views Visualization» more  IV 2008»
13 years 11 months ago
Revealing Subnetwork Roles using Contextual Visualization: Comparison of Metabolic Networks
This article is addressing a recurrent problem in biology: mining newly built large scale networks. Our approach consists in comparing these new networks to well known ones. The v...
Romain Bourqui, Fabien Jourdan
BMCBI
2010
86views more  BMCBI 2010»
13 years 4 months ago
Reaction graph kernels predict EC numbers of unknown enzymatic reactions in plant secondary metabolism
Background: Understanding of secondary metabolic pathway in plant is essential for finding druggable candidate enzymes. However, there are many enzymes whose functions are not yet...
Hiroto Saigo, Masahiro Hattori, Hisashi Kashima, K...
RECOMB
2010
Springer
13 years 9 months ago
SubMAP: Aligning Metabolic Pathways with Subnetwork Mappings
Abstract. We consider the problem of aligning two metabolic pathways. Unlike traditional approaches, we do not restrict the alignment to one-to-one mappings between the molecules o...
Ferhat Ay, Tamer Kahveci