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BMCBI
2005
108views more  BMCBI 2005»
13 years 5 months ago
The modeled structure of the RNA dependent RNA polymerase of GBV-C Virus suggests a role for motif E in Flaviviridae RNA polymer
Background: The Flaviviridae virus family includes major human and animal pathogens. The RNA dependent RNA polymerase (RdRp) plays a central role in the replication process, and t...
François Ferron, Cécile Bussetta, H&...
BMCBI
2005
136views more  BMCBI 2005»
13 years 5 months ago
Identification of clustered microRNAs using an ab initio prediction method
Background: MicroRNAs (miRNAs) are endogenous 21 to 23-nucleotide RNA molecules that regulate protein-coding gene expression in plants and animals via the RNA interference pathway...
Alain Sewer, Nicodème Paul, Pablo Landgraf,...
BMCBI
2006
137views more  BMCBI 2006»
13 years 5 months ago
Biologically relevant effects of mRNA amplification on gene expression profiles
Background: Gene expression microarray technology permits the analysis of global gene expression profiles. The amount of sample needed limits the use of small excision biopsies an...
Rachel I. M. van Haaften, Blanche Schroen, Ben J. ...
BMCBI
2010
131views more  BMCBI 2010»
13 years 2 months ago
A two-step site and mRNA-level model for predicting microRNA targets
Background: Despite experiments showing that the number of microRNA (miRNA) target sites is critical for miRNA targeting, most existing methods focus on identifying individual miR...
Takaya Saito, Pål Sætrom