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» GOChase: correcting errors from Gene Ontology-based annotati...
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BMCBI
2008
101views more  BMCBI 2008»
13 years 6 months ago
Scipio: Using protein sequences to determine the precise exon/intron structures of genes and their orthologs in closely related
Background: For many types of analyses, data about gene structure and locations of non-coding regions of genes are required. Although a vast amount of genomic sequence data is ava...
Oliver Keller, Florian Odronitz, Mario Stanke, Mar...
BMCBI
2006
122views more  BMCBI 2006»
13 years 6 months ago
Genome comparison using Gene Ontology (GO) with statistical testing
Background: Automated comparison of complete sets of genes encoded in two genomes can provide insight on the genetic basis of differences in biological traits between species. Gen...
Zhaotao Cai, Xizeng Mao, Songgang Li, Liping Wei
BMCBI
2005
80views more  BMCBI 2005»
13 years 6 months ago
Gene finding in the chicken genome
Background: Despite the continuous production of genome sequence for a number of organisms, reliable, comprehensive, and cost effective gene prediction remains problematic. This i...
Eduardo Eyras, Alexandre Reymond, Robert Castelo, ...
BMCBI
2010
105views more  BMCBI 2010»
13 years 6 months ago
Predicting phenotypic traits of prokaryotes from protein domain frequencies
Background: Establishing the relationship between an organism's genome sequence and its phenotype is a fundamental challenge that remains largely unsolved. Accurately predict...
Thomas Lingner, Stefanie Mühlhausen, Toni Gab...
BMCBI
2004
154views more  BMCBI 2004»
13 years 5 months ago
Base-By-Base: Single nucleotide-level analysis of whole viral genome alignments
Background: With ever increasing numbers of closely related virus genomes being sequenced, it has become desirable to be able to compare two genomes at a level more detailed than ...
Ryan Brodie, Alex J. Smith, Rachel L. Roper, Vasil...