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» GOtcha: a new method for prediction of protein function asse...
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BMCBI
2004
144views more  BMCBI 2004»
13 years 4 months ago
GOtcha: a new method for prediction of protein function assessed by the annotation of seven genomes
Background: The function of a novel gene product is typically predicted by transitive assignment of annotation from similar sequences. We describe a novel method, GOtcha, for pred...
David M. A. Martin, Matthew Berriman, Geoffrey J. ...
BMCBI
2006
169views more  BMCBI 2006»
13 years 4 months ago
Assessing protein similarity with Gene Ontology and its use in subnuclear localization prediction
Background: The accomplishment of the various genome sequencing projects resulted in accumulation of massive amount of gene sequence information. This calls for a large-scale comp...
Zhengdeng Lei, Yang Dai
JMLR
2010
133views more  JMLR 2010»
12 years 11 months ago
Hierarchical Cost-Sensitive Algorithms for Genome-Wide Gene Function Prediction
In this work we propose new ensemble methods for the hierarchical classification of gene functions. Our methods exploit the hierarchical relationships between the classes in diffe...
Nicolò Cesa-Bianchi, Giorgio Valentini
BMCBI
2006
207views more  BMCBI 2006»
13 years 4 months ago
A new measure for functional similarity of gene products based on Gene Ontology
Background: Gene Ontology (GO) is a standard vocabulary of functional terms and allows for coherent annotation of gene products. These annotations provide a basis for new methods ...
Andreas Schlicker, Francisco S. Domingues, Jö...
BMCBI
2005
173views more  BMCBI 2005»
13 years 4 months ago
Phydbac "Gene Function Predictor" : a gene annotation tool based on genomic context analysis
Background: The large amount of completely sequenced genomes allows genomic context analysis to predict reliable functional associations between prokaryotic proteins. Major method...
François Enault, Karsten Suhre, Jean-Michel...