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BMCBI
2011
13 years 2 days ago
Statistical Test of Expression Pattern (STEPath): a new strategy to integrate gene expression data with genomic information in i
Background: In the last decades, microarray technology has spread, leading to a dramatic increase of publicly available datasets. The first statistical tools developed were focuse...
Paolo G. V. Martini, Davide Risso, Gabriele Sales,...
BMCBI
2010
96views more  BMCBI 2010»
13 years 5 months ago
Incorporating gene co-expression network in identification of cancer prognosis markers
Background: Extensive biomedical studies have shown that clinical and environmental risk factors may not have sufficient predictive power for cancer prognosis. The development of ...
Shuangge Ma, Mingyu Shi, Yang Li, Danhui Yi, Ben-C...
SACI
2007
IEEE
13 years 11 months ago
A Computational Intelligence Approach for Ranking Risk Factors in Preterm Birth
- The aim of this paper is to propose a filter, based on a multi-objective evolutionary algorithm, for attributes’ ranking in the context of a data mining task. The behavior of t...
Daniela Zaharie, Stefan Holban, Diana Lungeanu, Da...
BMCBI
2005
102views more  BMCBI 2005»
13 years 5 months ago
Genome-wide identification of the regulatory targets of a transcription factor using biochemical characterization and computatio
Background: A major challenge in computational genomics is the development of methodologies that allow accurate genome-wide prediction of the regulatory targets of a transcription...
Emmitt R. Jolly, Chen-Shan Chin, Ira Herskowitz, H...
BMCBI
2008
143views more  BMCBI 2008»
13 years 5 months ago
Gene identification and protein classification in microbial metagenomic sequence data via incremental clustering
Background: The identification and study of proteins from metagenomic datasets can shed light on the roles and interactions of the source organisms in their communities. However, ...
Shibu Yooseph, Weizhong Li, Granger G. Sutton